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Japanese POEMS syndrome with Thalidomide (J-POST) Trial: study protocol for a phase II/III multicentre, randomised, double-blind, placebo-controlled trial

INTRODUCTION: Polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes (POEMS) syndrome is a fatal systemic disorder associated with plasma cell dyscrasia and the overproduction of the vascular endothelial growth factor (VEGF). Recently, the prognosis of POEMS was substantially impro...

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Detalles Bibliográficos
Autores principales: Katayama, Kanako, Misawa, Sonoko, Sato, Yasunori, Sobue, Gen, Yabe, Ichiro, Watanabe, Osamu, Nishizawa, Masatoyo, Kusunoki, Susumu, Kikuchi, Seiji, Nakashima, Ichiro, Ikeda, Shu-ichi, Kohara, Nobuo, Kanda, Takashi, Kira, Jun-ichi, Hanaoka, Hideki, Kuwabara, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289734/
https://www.ncbi.nlm.nih.gov/pubmed/25573527
http://dx.doi.org/10.1136/bmjopen-2014-007330