Non-viral immune electrogene therapy induces potent antitumour responses and has a curative effect in murine colon adenocarcinoma and melanoma cancer models

Antitumour efficacy of electroporated pEEV, coding for granulocyte–macrophage colony-stimulating factor and the B7-1 costimulatory immune molecule (pEEVGmCSF-b7.1) in growing solid tumours, was investigated and compared with a standard plasmid. Application of pEEVGmCSF-b7.1 led to complete tumour re...

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Detalles Bibliográficos
Autores principales: Forde, P F, Hall, L J, de Kruijf, M, Bourke, M G, Doddy, T, Sadadcharam, M, Soden, D M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289754/
https://www.ncbi.nlm.nih.gov/pubmed/25373914
http://dx.doi.org/10.1038/gt.2014.95

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289754/
https://www.ncbi.nlm.nih.gov/pubmed/25373914
http://dx.doi.org/10.1038/gt.2014.95

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