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Premature Senescence in Primary Muscle Cultures of Myotonic Dystrophy Type 2 is not Associated with p16 Induction

Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are multisystemic disorders linked to two different genetic loci and characterized by several features including myotonia, muscle weakness and atrophy, cardiac dysfunctions, cataracts and insulin-resistance. In both forms, expanded nucleotide sequence...

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Detalles Bibliográficos
Autores principales: Renna, L.V., Cardani, R., Botta, A., Rossi, G., Fossati, B., Costa, E., Meola, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289846/
https://www.ncbi.nlm.nih.gov/pubmed/25578974
http://dx.doi.org/10.4081/ejh.2014.2444