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Heterogeneous sensitivity of human Acute Myeloid Leukemia to ß-catenin down-modulation
Dysregulation of the Wnt/ß-catenin pathway has been observed in various malignancies, including acute myeloid leukemia (AML), where the over-expression of ß-catenin is an independent adverse prognostic factor. ß-catenin was found up-regulated in the vast majority of AML samples and more frequently l...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289854/ https://www.ncbi.nlm.nih.gov/pubmed/21339756 http://dx.doi.org/10.1038/leu.2011.17 |