Method for quantitative analysis of nonsense-mediated mRNA decay at the single cell level

Nonsense-mediated mRNA decay (NMD) is a ubiquitous mechanism of degradation of transcripts with a premature termination codon. NMD eliminates aberrant mRNA species derived from sources of genetic variation such as gene mutations, alternative splicing and DNA rearrangements in immune cells. In additi...

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Detalles Bibliográficos
Autores principales: Pereverzev, Anton P., Gurskaya, Nadya G., Ermakova, Galina V., Kudryavtseva, Elena I., Markina, Nadezhda M., Kotlobay, Alexey A., Lukyanov, Sergey A., Zaraisky, Andrey G., Lukyanov, Konstantin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289894/
https://www.ncbi.nlm.nih.gov/pubmed/25578556
http://dx.doi.org/10.1038/srep07729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289894/
https://www.ncbi.nlm.nih.gov/pubmed/25578556
http://dx.doi.org/10.1038/srep07729

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