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Method for quantitative analysis of nonsense-mediated mRNA decay at the single cell level
Nonsense-mediated mRNA decay (NMD) is a ubiquitous mechanism of degradation of transcripts with a premature termination codon. NMD eliminates aberrant mRNA species derived from sources of genetic variation such as gene mutations, alternative splicing and DNA rearrangements in immune cells. In additi...
Autores principales: | Pereverzev, Anton P., Gurskaya, Nadya G., Ermakova, Galina V., Kudryavtseva, Elena I., Markina, Nadezhda M., Kotlobay, Alexey A., Lukyanov, Sergey A., Zaraisky, Andrey G., Lukyanov, Konstantin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289894/ https://www.ncbi.nlm.nih.gov/pubmed/25578556 http://dx.doi.org/10.1038/srep07729 |
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