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Using hidden Markov models to investigate G-quadruplex motifs in genomic sequences
BACKGROUND: G-quadruplexes are four-stranded structures formed in guanine-rich nucleotide sequences. Several functional roles of DNA G-quadruplexes have so far been investigated, where their putative functional roles during DNA replication and transcription have been suggested. A necessary condition...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290599/ https://www.ncbi.nlm.nih.gov/pubmed/25521044 http://dx.doi.org/10.1186/1471-2164-15-S9-S15 |