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Using hidden Markov models to investigate G-quadruplex motifs in genomic sequences

BACKGROUND: G-quadruplexes are four-stranded structures formed in guanine-rich nucleotide sequences. Several functional roles of DNA G-quadruplexes have so far been investigated, where their putative functional roles during DNA replication and transcription have been suggested. A necessary condition...

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Detalles Bibliográficos
Autores principales: Yano, Masato, Kato, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290599/
https://www.ncbi.nlm.nih.gov/pubmed/25521044
http://dx.doi.org/10.1186/1471-2164-15-S9-S15