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Predicting sumoylation sites using support vector machines based on various sequence features, conformational flexibility and disorder

BACKGROUND: Sumoylation, which is a reversible and dynamic post-translational modification, is one of the vital processes in a cell. Before a protein matures to perform its function, sumoylation may alter its localization, interactions, and possibly structural conformation. Abberations in protein su...

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Detalles Bibliográficos
Autores principales: Yavuz, Ahmet Sinan, Sezerman, Osman Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290605/
https://www.ncbi.nlm.nih.gov/pubmed/25521314
http://dx.doi.org/10.1186/1471-2164-15-S9-S18