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Computational identification of novel natural inhibitors of glucagon receptor for checking type II diabetes mellitus
BACKGROUND: Interaction of the small peptide hormone glucagon with glucagon receptor (GCGR) stimulates the release of glucose from the hepatic cells during fasting; hence GCGR performs a significant function in glucose homeostasis. Inhibiting the interaction between glucagon and its receptor has bee...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290642/ https://www.ncbi.nlm.nih.gov/pubmed/25521597 http://dx.doi.org/10.1186/1471-2105-15-S16-S13 |