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Computational identification of novel natural inhibitors of glucagon receptor for checking type II diabetes mellitus

BACKGROUND: Interaction of the small peptide hormone glucagon with glucagon receptor (GCGR) stimulates the release of glucose from the hepatic cells during fasting; hence GCGR performs a significant function in glucose homeostasis. Inhibiting the interaction between glucagon and its receptor has bee...

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Detalles Bibliográficos
Autores principales: Grover, Sonam, Dhanjal, Jaspreet Kaur, Goyal, Sukriti, Grover, Abhinav, Sundar, Durai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290642/
https://www.ncbi.nlm.nih.gov/pubmed/25521597
http://dx.doi.org/10.1186/1471-2105-15-S16-S13