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Endothelin@25 – new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12

Since the discovery of endothelin (ET)-1 in 1988, the main components of the signalling pathway have become established, comprising three structurally similar endogenous 21-amino acid peptides, ET-1, ET-2 and ET-3, that activate two GPCRs, ET(A) and ET(B). Our aim in this review is to highlight the...

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Detalles Bibliográficos
Autores principales: Maguire, J J, Davenport, A P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290702/
https://www.ncbi.nlm.nih.gov/pubmed/25131455
http://dx.doi.org/10.1111/bph.12874