The Size of the Internal Loop in DNA Hairpins Influences Their Targeting with Partially Complementary Strands

[Image: see text] Targeting of noncanonical DNA structures, such as hairpin loops, may have significant diagnostic and therapeutic potential. Oligonucleotides can be used for binding to mRNA, forming a DNA/RNA hybrid duplex that inhibits translation. This kind of modulation of gene expression is cal...

Descripción completa

Detalles Bibliográficos
Autores principales: Prislan, Iztok, Lee, Hui-Ting, Lee, Cynthia, Marky, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291056/
https://www.ncbi.nlm.nih.gov/pubmed/25486129
http://dx.doi.org/10.1021/jp510131c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291056/
https://www.ncbi.nlm.nih.gov/pubmed/25486129
http://dx.doi.org/10.1021/jp510131c

Ejemplares similares