Cargando…
The Size of the Internal Loop in DNA Hairpins Influences Their Targeting with Partially Complementary Strands
[Image: see text] Targeting of noncanonical DNA structures, such as hairpin loops, may have significant diagnostic and therapeutic potential. Oligonucleotides can be used for binding to mRNA, forming a DNA/RNA hybrid duplex that inhibits translation. This kind of modulation of gene expression is cal...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291056/ https://www.ncbi.nlm.nih.gov/pubmed/25486129 http://dx.doi.org/10.1021/jp510131c |