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Ex Vivo Characterization of a Novel Iodine-123-Labelled Aminomethylchroman as a Potential Agonist Ligand for SPECT Imaging of Dopamine D(2/3) Receptors

For imaging of dopamine D(2/3) receptors, agonist tracers are favoured over antagonists because they are more sensitive to detection of dopamine release and because they may selectively label the high-affinity receptor state. We have developed novel D(2/3) receptor selective agonists that can be rad...

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Detalles Bibliográficos
Autores principales: van Wieringen, Jan-Peter, de Bruin, Kora, Janssen, Henk M., Fransen, P. Michel, Janssen, Anton G. M., van Doremalen, Peter A., Michel, Martin C., Elsinga, Philip H., Booij, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291083/
https://www.ncbi.nlm.nih.gov/pubmed/25610643
http://dx.doi.org/10.1155/2014/507012