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A High-Throughput Assay for Arylamine Halogenation Based on a Peroxidase-Mediated Quinone–Amine Coupling with Applications in the Screening of Enzymatic Halogenations

Arylhalides are important building blocks in many fine chemicals, pharmaceuticals and agrochemicals, and there has been increasing interest in the development of more “green” halogenation methods based on enzyme catalysis. However, the screening and development of new enzymes for biohalogenation has...

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Detalles Bibliográficos
Autores principales: Hosford, Joseph, Shepherd, Sarah A, Micklefield, Jason, Wong, Lu Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291110/
https://www.ncbi.nlm.nih.gov/pubmed/25319801
http://dx.doi.org/10.1002/chem.201403953