Inhibitors of CLK Protein Kinases Suppress Cell Growth and Induce Apoptosis by Modulating Pre-mRNA Splicing

Accumulating evidence has demonstrated the importance of alternative splicing in various physiological processes, including the development of different diseases. CDC-like kinases (CLKs) and serine-arginine protein kinases (SRPKs) are components of the splicing machinery that are crucial for exon se...

Descripción completa

Detalles Bibliográficos
Autores principales: Araki, Shinsuke, Dairiki, Ryo, Nakayama, Yusuke, Murai, Aiko, Miyashita, Risa, Iwatani, Misa, Nomura, Toshiyuki, Nakanishi, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291223/
https://www.ncbi.nlm.nih.gov/pubmed/25581376
http://dx.doi.org/10.1371/journal.pone.0116929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291223/
https://www.ncbi.nlm.nih.gov/pubmed/25581376
http://dx.doi.org/10.1371/journal.pone.0116929

Ejemplares similares