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RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity

Formation of a new centriole adjacent to a pre-existing centriole occurs only once per cell cycle. Despite being crucial for genome integrity, the mechanisms controlling centriole biogenesis remain elusive. Here, we identify RBM14 as a novel suppressor of assembly of centriolar protein complexes. De...

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Detalles Bibliográficos
Autores principales: Shiratsuchi, Gen, Takaoka, Katsuyoshi, Ashikawa, Tomoko, Hamada, Hiroshi, Kitagawa, Daiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291483/
https://www.ncbi.nlm.nih.gov/pubmed/25385835
http://dx.doi.org/10.15252/embj.201488979