Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element

Gene regulation relies on dynamic changes in three-dimensional chromatin conformation, which are shaped by composite regulatory and architectural elements. However, mechanisms that govern such conformational switches within chromosomal domains remain unknown. We identify a novel mechanism by which c...

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Detalles Bibliográficos
Autores principales: Majumder, Kinjal, Koues, Olivia I., Chan, Elizabeth A.W., Kyle, Katherine E., Horowitz, Julie E., Yang-Iott, Katherine, Bassing, Craig H., Taniuchi, Ichiro, Krangel, Michael S., Oltz, Eugene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291525/
https://www.ncbi.nlm.nih.gov/pubmed/25512470
http://dx.doi.org/10.1084/jem.20141479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291525/
https://www.ncbi.nlm.nih.gov/pubmed/25512470
http://dx.doi.org/10.1084/jem.20141479

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