Bioorthogonal Tetrazine-Mediated Transfer Reactions Facilitate Reaction Turnover in Nucleic Acid-Templated Detection of MicroRNA

[Image: see text] Tetrazine ligations have proven to be a powerful bioorthogonal technique for the detection of many labeled biomolecules, but the ligating nature of these reactions can limit reaction turnover in templated chemistry. We have developed a transfer reaction between 7-azabenzonorbornadi...

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Detalles Bibliográficos
Autores principales: Wu, Haoxing, Cisneros, Brandon T., Cole, Christian M., Devaraj, Neal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291768/
https://www.ncbi.nlm.nih.gov/pubmed/25495860
http://dx.doi.org/10.1021/ja510839r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291768/
https://www.ncbi.nlm.nih.gov/pubmed/25495860
http://dx.doi.org/10.1021/ja510839r

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