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Relating Toxicity to Transfection: Using Sphingosine To Maintain Prolonged Expression in Vitro

[Image: see text] Cationic reagents are commonly used to facilitate DNA delivery, and transfection experiments are typically initiated in cell culture where the optimal charge ratio is determined. While transfection rates are often enhanced at higher +/– charge ratios, the cellular toxicity associat...

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Detalles Bibliográficos
Autores principales: Betker, Jamie L., Anchordoquy, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291780/
https://www.ncbi.nlm.nih.gov/pubmed/25418523
http://dx.doi.org/10.1021/mp500604r