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Relating Toxicity to Transfection: Using Sphingosine To Maintain Prolonged Expression in Vitro
[Image: see text] Cationic reagents are commonly used to facilitate DNA delivery, and transfection experiments are typically initiated in cell culture where the optimal charge ratio is determined. While transfection rates are often enhanced at higher +/– charge ratios, the cellular toxicity associat...
Autores principales: | Betker, Jamie L., Anchordoquy, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291780/ https://www.ncbi.nlm.nih.gov/pubmed/25418523 http://dx.doi.org/10.1021/mp500604r |
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