Hepatic Metabolism Affects the Atropselective Disposition of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) in Mice

[Image: see text] To understand the role of hepatic vs extrahepatic metabolism in the disposition of chiral PCBs, we studied the disposition of 2,2′,3,3′,6,6′-hexachlorobiphenyl (PCB 136) and its hydroxylated metabolites (HO-PCBs) in mice with defective hepatic metabolism due to the liver-specific d...

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Detalles Bibliográficos
Autores principales: Wu, Xianai, Barnhart, Christopher, Lein, Pamela J., Lehmler, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291784/
https://www.ncbi.nlm.nih.gov/pubmed/25420130
http://dx.doi.org/10.1021/es504766p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291784/
https://www.ncbi.nlm.nih.gov/pubmed/25420130
http://dx.doi.org/10.1021/es504766p

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