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Loss of E-cadherin and epithelial to mesenchymal transition is not required for cell motility in tissues or for metastasis
Loss of E-cadherin has been long considered to be a major hallmark of epithelial-mesenchymal transition (EMT) and has been reported in various cancers. P120 catenin regulates E-cadherin stability on the cell surface and also plays a role in intracellular signaling by modulating nuclear transcription...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292045/ https://www.ncbi.nlm.nih.gov/pubmed/25610757 http://dx.doi.org/10.4161/21688362.2014.969112 |