The phosphoinositide-binding protein TRAF4 modulates tight junction stability and migration of cancer cells

Tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4), a protein localized in TJs in normal epithelial cells, is frequently overexpressed in carcinomas. We recently found that TRAF4 impedes TJ formation/stability and favors cell migration, 2 hallmarks of cancer progression. In addition TR...

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Detalles Bibliográficos
Autores principales: Rousseau, Adrien, Wilhelm, Léa P, Tomasetto, Catherine, Alpy, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292048/
https://www.ncbi.nlm.nih.gov/pubmed/25610759
http://dx.doi.org/10.4161/21688370.2014.975597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292048/
https://www.ncbi.nlm.nih.gov/pubmed/25610759
http://dx.doi.org/10.4161/21688370.2014.975597

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