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STAT3 Single Nucleotide Polymorphism rs4796793 SNP Does Not Correlate with Response to Adjuvant IFNα Therapy in Stage III Melanoma Patients

Interferon alpha (IFNα) is approved for adjuvant treatment of stage III melanoma in Europe and the US. Its clinical efficacy, however, is restricted to a subpopulation of patients while side effects occur in most of treated patients. Thus, the identification of predictive biomarkers would be highly...

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Detalles Bibliográficos
Autores principales: Schrama, David, Ugurel, Selma, Sucker, Antje, Ritter, Cathrin, Zapatka, Marc, Schadendorf, Dirk, Becker, Jürgen Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292185/
https://www.ncbi.nlm.nih.gov/pubmed/25593920
http://dx.doi.org/10.3389/fmed.2014.00047