Utilising Family-Based Designs for Detecting Rare Variant Disease Associations

Rare genetic variants are thought to be important components in the causality of many diseases but discovering these associations is challenging. We demonstrate how best to use family-based designs to improve the power to detect rare variant disease associations. We show that using genetic data from...

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Detalles Bibliográficos
Autores principales: Preston, Mark D, Dudbridge, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292528/
https://www.ncbi.nlm.nih.gov/pubmed/24571231
http://dx.doi.org/10.1111/ahg.12051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292528/
https://www.ncbi.nlm.nih.gov/pubmed/24571231
http://dx.doi.org/10.1111/ahg.12051

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