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The Effect of Interference on the CD8(+) T Cell Escape Rates in HIV

In early human immunodeficiency virus (HIV) infection, the virus population escapes from multiple CD8(+) cell responses. The later an escape mutation emerges, the slower it outgrows its competition, i.e., the escape rate is lower. This pattern could indicate that the strength of the CD8(+) cell resp...

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Detalles Bibliográficos
Autores principales: Garcia, Victor, Regoes, Roland Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292734/
https://www.ncbi.nlm.nih.gov/pubmed/25628620
http://dx.doi.org/10.3389/fimmu.2014.00661