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CYP1B1 enhances the resistance of epithelial ovarian cancer cells to paclitaxel in vivo and in vitro
Ovarian cancer (OC) is the most frequent cause of mortality among gynecological malignancies, with a 5-year survival rate of approximately 30%. The standard regimen for OC therapy includes a platinum agent combined with a taxane, to which the patients frequently acquire resistance. Resistance arises...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292762/ https://www.ncbi.nlm.nih.gov/pubmed/25516145 http://dx.doi.org/10.3892/ijmm.2014.2041 |