The thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and PI3K pathways in rabbit articular chondrocytes

Dedifferentiation and inflammation are major features of cartilage degeneration during the pathogenesis of osteoarthritis (OA). Thymoquinone (TQ) is the major compound of black seed oil isolated from Nigella sativa with various beneficial or harmful effects on several diseases; however, its effects...

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Detalles Bibliográficos
Autores principales: YU, SEON-MI, KIM, SONG-JA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292767/
https://www.ncbi.nlm.nih.gov/pubmed/25435376
http://dx.doi.org/10.3892/ijmm.2014.2014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292767/
https://www.ncbi.nlm.nih.gov/pubmed/25435376
http://dx.doi.org/10.3892/ijmm.2014.2014

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