New genetic variants of LATS1 detected in urinary bladder and colon cancer

LATS1, the large tumor suppressor 1 gene, encodes for a serine/threonine kinase protein and is implicated in cell cycle progression. LATS1 is down-regulated in various human cancers, such as breast cancer, and astrocytoma. Point mutations in LATS1 were reported in human sarcomas. Additionally, loss...

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Detalles Bibliográficos
Autores principales: Saadeldin, Mona K., Shawer, Heba, Mostafa, Ahmed, Kassem, Neemat M., Amleh, Asma, Siam, Rania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292772/
https://www.ncbi.nlm.nih.gov/pubmed/25628642
http://dx.doi.org/10.3389/fgene.2014.00425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292772/
https://www.ncbi.nlm.nih.gov/pubmed/25628642
http://dx.doi.org/10.3389/fgene.2014.00425

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