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Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs)

Homoharringtonine (HHT) has been widely used in China to treat patients with acute and chronic myeloid leukemia for decades. Since response to HHT varies among patients, our study aimed to identify biomarkers that might influence the response to HHT using a panel of various human lymphoblastoid cell...

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Detalles Bibliográficos
Autores principales: Tong, Yin, Niu, Nifang, Jenkins, Gregory, Batzler, Anthony, Li, Liang, Kalari, Krishna R., Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292778/
https://www.ncbi.nlm.nih.gov/pubmed/25628645
http://dx.doi.org/10.3389/fgene.2014.00465