Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53

BACKGROUND: Understanding how inflammation causes neuronal damage is of paramount importance in multiple sclerosis (MS) and in other neurodegenerative diseases. Here we addressed the role of the apoptotic cascade in the synaptic abnormalities and neuronal loss caused by the proinflammatory cytokines...

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Detalles Bibliográficos
Autores principales: Rossi, Silvia, Motta, Caterina, Studer, Valeria, Macchiarulo, Giulia, Volpe, Elisabetta, Barbieri, Francesca, Ruocco, Gabriella, Buttari, Fabio, Finardi, Annamaria, Mancino, Raffaele, Weiss, Sagit, Battistini, Luca, Martino, Gianvito, Furlan, Roberto, Drulovic, Jelena, Centonze, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292815/
https://www.ncbi.nlm.nih.gov/pubmed/25495224
http://dx.doi.org/10.1186/1750-1326-9-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292815/
https://www.ncbi.nlm.nih.gov/pubmed/25495224
http://dx.doi.org/10.1186/1750-1326-9-56

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