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Transcriptome-wide signatures of tumor stage in kidney renal clear cell carcinoma: connecting copy number variation, methylation and transcription factor activity

BACKGROUND: Comparative analysis of expression profiles between early and late stage cancers can help to understand cancer progression and metastasis mechanisms and to predict the clinical aggressiveness of cancer. The observed stage-dependent expression changes can be explained by genetic and epige...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Su, Pei-Fang, Zhao, Shilin, Shyr, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293006/
https://www.ncbi.nlm.nih.gov/pubmed/25648588
http://dx.doi.org/10.1186/s13073-014-0117-z