Large interdomain rearrangement triggered by suppression of micro- to millisecond dynamics in bacterial Enzyme I

Enzyme I (EI), the first component of the bacterial phosphotransfer signal transduction system, undergoes one of the largest substrate-induced interdomain rearrangements documented to date. Here, we characterize the perturbations generated by two small molecules, the natural substrate phosphoenolpyr...

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Detalles Bibliográficos
Autores principales: Venditti, Vincenzo, Tugarinov, Vitali, Schwieters, Charles D., Grishaev, Alexander, Clore, G. Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293084/
https://www.ncbi.nlm.nih.gov/pubmed/25581904
http://dx.doi.org/10.1038/ncomms6960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293084/
https://www.ncbi.nlm.nih.gov/pubmed/25581904
http://dx.doi.org/10.1038/ncomms6960

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