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Combined Use of Mycobacterium tuberculosis–Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis

Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tube...

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Detalles Bibliográficos
Autores principales: Rozot, Virginie, Patrizia, Amelio, Vigano, Selena, Mazza-Stalder, Jesica, Idrizi, Elita, Day, Cheryl L., Perreau, Matthieu, Lazor-Blanchet, Catherine, Ohmiti, Khalid, Goletti, Delia, Bart, Pierre-Alexandre, Hanekom, Willem, Scriba, Thomas J., Nicod, Laurent, Pantaleo, Giuseppe, Harari, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293395/
https://www.ncbi.nlm.nih.gov/pubmed/25362202
http://dx.doi.org/10.1093/cid/ciu795