A potent tumoricidal co-drug ‘Bet-CA' - an ester derivative of betulinic acid and dichloroacetate selectively and synergistically kills cancer cells

Selective targeting of cancer cells employing multiple combinations as co-drug holds promise for new generation therapeutics. Betulinic acid (BA), a plant secondary metabolite kills cancer cells and Dichloroacetate (DCA) is capable of reversing the Warburg phenotype by inhibiting pyruvate dehydrogen...

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Detalles Bibliográficos
Autores principales: Saha, Suchandrima, Ghosh, Monisankar, Dutta, Samir Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293591/
https://www.ncbi.nlm.nih.gov/pubmed/25585916
http://dx.doi.org/10.1038/srep07762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293591/
https://www.ncbi.nlm.nih.gov/pubmed/25585916
http://dx.doi.org/10.1038/srep07762

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