NQO1-induced activation of AMPK contributes to cancer cell death by oxygen-glucose deprivation

Oxygen and glucose deprivation (OGD) due to insufficient blood circulation can decrease cancer cell survival and proliferation in solid tumors. OGD increases the intracellular [AMP]/[ATP] ratio, thereby activating the AMPK. In this study, we have investigated the involvement of NQO1 in OGD-mediated...

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Detalles Bibliográficos
Autores principales: Lee, Hyemi, Oh, Eun-Taex, Choi, Bo-Hwa, Park, Moon-Taek, Lee, Ja-Kyeong, Lee, Jae-Seon, Park, Heon Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293602/
https://www.ncbi.nlm.nih.gov/pubmed/25586669
http://dx.doi.org/10.1038/srep07769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293602/
https://www.ncbi.nlm.nih.gov/pubmed/25586669
http://dx.doi.org/10.1038/srep07769

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