Co-immunization with DNA and protein mixture: A safe and efficacious immunotherapeutic strategy for Alzheimer's disease in PDAPP mice

Active immunotherapy targeting β-amyloid (Aβ) is the most promising strategy to prevent or treat Alzheimer's disease (AD). Based on pre-clinical studies and clinical trials, a safe and effective AD vaccine requires a delicate balance between providing therapeutically adequate anti-Aβ antibodies...

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Detalles Bibliográficos
Autores principales: Liu, Si, Shi, DanYang, Wang, Hai-Chao, Yu, Yun-Zhou, Xu, Qing, Sun, Zhi-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293606/
https://www.ncbi.nlm.nih.gov/pubmed/25586780
http://dx.doi.org/10.1038/srep07771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293606/
https://www.ncbi.nlm.nih.gov/pubmed/25586780
http://dx.doi.org/10.1038/srep07771

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