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Hyperglycemia Inhibits Complement-Mediated Immunological Control of S. aureus in a Rat Model of Peritonitis

Hyperglycemia from diabetes is associated with increased risk of infection from S. aureus and increased severity of illness. Previous work in our laboratory demonstrated that elevated glucose (>6 mM) dramatically inhibited S. aureus-initiated complement-mediated immune effectors. Here we report i...

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Detalles Bibliográficos
Autores principales: Mauriello, Clifford T., Hair, Pamela S., Rohn, Reuben D., Rister, Nicholas S., Krishna, Neel K., Cunnion, Kenji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293792/
https://www.ncbi.nlm.nih.gov/pubmed/25610878
http://dx.doi.org/10.1155/2014/762051