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Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma

BACKGROUND: Most patients with small cell lung cancer (SCLC) or neuroblastoma (NB) already show clinically detectable metastases at diagnosis and have an extremely poor prognosis even when treated with combined modalities. The HuD-antigen is a neuronal RNA-binding protein that is expressed in 100% o...

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Detalles Bibliográficos
Autores principales: Ehrlich, Debra, Wang, Bo, Lu, Wei, Dowling, Peter, Yuan, Ruirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293823/
https://www.ncbi.nlm.nih.gov/pubmed/25523825
http://dx.doi.org/10.1186/s13045-014-0091-3