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Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma
BACKGROUND: Most patients with small cell lung cancer (SCLC) or neuroblastoma (NB) already show clinically detectable metastases at diagnosis and have an extremely poor prognosis even when treated with combined modalities. The HuD-antigen is a neuronal RNA-binding protein that is expressed in 100% o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293823/ https://www.ncbi.nlm.nih.gov/pubmed/25523825 http://dx.doi.org/10.1186/s13045-014-0091-3 |