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Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage

BACKGROUND: Lipids are stored within cells in lipid droplets (LDs). They consist of a core of neutral lipids surrounded by a monolayer of phospholipids, predominantly phosphatidylcholine (PC). LDs are very dynamic and can rapidly change in size upon lipid uptake or release. These dynamics require a...

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Detalles Bibliográficos
Autores principales: Moessinger, Christine, Klizaite, Kristina, Steinhagen, Almut, Philippou-Massier, Julia, Shevchenko, Andrej, Hoch, Michael, Ejsing, Christer S, Thiele, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293825/
https://www.ncbi.nlm.nih.gov/pubmed/25491198
http://dx.doi.org/10.1186/s12860-014-0043-3