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Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage
BACKGROUND: Lipids are stored within cells in lipid droplets (LDs). They consist of a core of neutral lipids surrounded by a monolayer of phospholipids, predominantly phosphatidylcholine (PC). LDs are very dynamic and can rapidly change in size upon lipid uptake or release. These dynamics require a...
Autores principales: | Moessinger, Christine, Klizaite, Kristina, Steinhagen, Almut, Philippou-Massier, Julia, Shevchenko, Andrej, Hoch, Michael, Ejsing, Christer S, Thiele, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293825/ https://www.ncbi.nlm.nih.gov/pubmed/25491198 http://dx.doi.org/10.1186/s12860-014-0043-3 |
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