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The Antiviral Effect of High-Molecular Weight Poly-Gamma-Glutamate against Newcastle Disease Virus on Murine Macrophage Cells

This study demonstrates the capacity of HM-γ-PGA treatment to significantly protect murine macrophage cells (RAW 264.7 cells) against NDV infection. Such protection can be explained by the induction of antiviral state of HM-γ-PGA in RAW 264.7 cells via TLR4-mediated IRF-3, IRF-7, IFN-β, and IFN-rela...

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Detalles Bibliográficos
Autores principales: Talactac, Melbourne, Lee, Jong-Soo, Moon, Hojin, Chowdhury, Mohammed Y. E., Kim, Chul Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293867/
https://www.ncbi.nlm.nih.gov/pubmed/25610463
http://dx.doi.org/10.1155/2014/301386