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A novel anti-proliferative role of HMGA2 in induction of apoptosis through caspase 2 in primary human fibroblast cells

The HMGA2 (high-mobility group AT-hook) protein has previously been shown as an oncoprotein, whereas ectopic expression of HMGA2 is found to induce growth arrest in primary cells. The precise mechanisms underlying this phenomenon remain to be unravelled. In the present study, we determined that HMGA...

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Detalles Bibliográficos
Autores principales: Shi, Xi, Tian, Baoqing, Ma, Wenlong, Zhang, Na, Qiao, Yuehua, Li, Xiaoxue, Zhang, Yu, Huang, Baiqu, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293904/
https://www.ncbi.nlm.nih.gov/pubmed/25300915
http://dx.doi.org/10.1042/BSR20140112