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Population pharmacokinetic–pharmacodynamic modelling in oncology: a tool for predicting clinical response

In oncology trials, overall survival (OS) is considered the most reliable and preferred endpoint to evaluate the benefit of drug treatment. Other relevant variables are also collected from patients for a given drug and its indication, and it is important to characterize the dynamic effects and links...

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Detalles Bibliográficos
Autores principales: Bender, Brendan C, Schindler, Emilie, Friberg, Lena E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294077/
https://www.ncbi.nlm.nih.gov/pubmed/24134068
http://dx.doi.org/10.1111/bcp.12258