Dual MMP7-Proximity-Activated and Folate Receptor-Targeted Nanoparticles for siRNA Delivery

[Image: see text] A dual-targeted siRNA nanocarrier has been synthesized and validated that is selectively activated in environments where there is colocalization of two breast cancer hallmarks, elevated matrix metalloproteinase (MMP) activity and folate receptor overexpression. This siRNA nanocarri...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hongmei, Miteva, Martina, Kirkbride, Kellye C., Cheng, Ming J., Nelson, Christopher E., Simpson, Elaine M., Gupta, Mukesh K., Duvall, Craig L., Giorgio, Todd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294138/
https://www.ncbi.nlm.nih.gov/pubmed/25414930
http://dx.doi.org/10.1021/bm501394m

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294138/
https://www.ncbi.nlm.nih.gov/pubmed/25414930
http://dx.doi.org/10.1021/bm501394m

Ejemplares similares