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The pathophysiology of extracellular hemoglobin associated with enhanced oxidative reactions
Hemoglobin (Hb) continuously undergoes autoxidation producing superoxide which dismutates into hydrogen peroxide (H(2)O(2)) and is a potential source for subsequent oxidative reactions. Autoxidation is most pronounced under hypoxic conditions in the microcirculation and for unstable dimers formed at...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294139/ https://www.ncbi.nlm.nih.gov/pubmed/25642190 http://dx.doi.org/10.3389/fphys.2014.00500 |