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Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi

Genomics has revolutionized the research on fungal secondary metabolite (SM) biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the biosynthesis of a specific SM compound, the important first step is often to find the genes that responsible for its synthesis. The accessibil...

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Detalles Bibliográficos
Autores principales: Cacho, Ralph A., Tang, Yi, Chooi, Yit-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294208/
https://www.ncbi.nlm.nih.gov/pubmed/25642215
http://dx.doi.org/10.3389/fmicb.2014.00774