The Class I Histone Deacetylase Inhibitor MS-275 Prevents Pancreatic Beta Cell Death Induced by Palmitate

Elevation of the dietary saturated fatty acid palmitate contributes to the reduction of functional beta cell mass in the pathogenesis of type 2 diabetes. The diabetogenic effect of palmitate is achieved by increasing beta cell death through induction of the endoplasmic reticulum (ER) stress markers...

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Detalles Bibliográficos
Autores principales: Plaisance, Valérie, Rolland, Laure, Gmyr, Valéry, Annicotte, Jean-Sébastien, Kerr-Conte, Julie, Pattou, François, Abderrahmani, Amar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294305/
https://www.ncbi.nlm.nih.gov/pubmed/25610877
http://dx.doi.org/10.1155/2014/195739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294305/
https://www.ncbi.nlm.nih.gov/pubmed/25610877
http://dx.doi.org/10.1155/2014/195739

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