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IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant desmoplastic reaction driven by pancreatic stellate cells (PSCs) that contributes to tumor progression. Here we sought to characterize the interactions between pancreatic cancer cells (PCCs) and PSCs that affect the inflammatory...

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Detalles Bibliográficos
Autores principales: Lunardi, Serena, Jamieson, Nigel B., Lim, Su Yin, Griffiths, Kristin L., Carvalho-Gaspar, Manuela, Al-Assar, Osama, Yameen, Sabira, Carter, Ross C., McKay, Colin J., Spoletini, Gabriele, D'Ugo, Stefano, Silva, Michael A., Sansom, Owen J., Janssen, Klaus-Peter, Muschel, Ruth J., Brunner, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294325/
https://www.ncbi.nlm.nih.gov/pubmed/25415223