Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition

Docetaxel (DTX) is a useful chemotherapeutic drug for the treatment of hormone-refractory prostate cancer. However, emergence of DTX resistance has been a therapeutic hurdle. In this study, we investigated the effect of combining DTX with Bcl-2 family inhibitors using human prostate cancer cell line...

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Detalles Bibliográficos
Autores principales: Tamaki, Hiroki, Harashima, Nanae, Hiraki, Miho, Arichi, Naoko, Nishimura, Nobuhiro, Shiina, Hiroaki, Naora, Kohji, Harada, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294332/
https://www.ncbi.nlm.nih.gov/pubmed/25333266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294332/
https://www.ncbi.nlm.nih.gov/pubmed/25333266

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